Cladribine, Litak, 10 mg (Biodribin,10 mg), Certificate of quality

Delivery time is 24 hours. The drug is shipped from Europe in a special container. Observed temperature Is 2-8 ░ C. pharmacy invoice of purchase of the drug in the EU.CERTIFICATE OF QUALITY! Cladribine International nonproprietary name of the active substance is a basic information about the drug. The fact that, as a rule, drugs with the same active ingredient manufactured under different trade names. It INN allows doctors to Orient in a huge number of drugs available in the pharmaceutical market. Drug name in English:CLADIRIBINE Pharmacological action: Analogue of 2'-deoxyadenosine that is part of the DNA molecule. Cladribine shows cytotoxic effects (due to active metabolite 5'-triphosphate-2-chloro-2'-deoxyadenosine) in respect of dividing and nondividing cells by inhibiting synthesis and DNA repair (inhibits ribonucleotide reductase, catalyzing the reaction of formation of deoxynucleoside, DNA polymerase and activates specific endonuclease, leading to single stranded breaks of DNA) that ultimately leads to cell death. The lymphoid cells more sensitive to the drug ( because they have a higher level of deoxycytidylate and a low level of activity of 5'-nucleotidase) than non-lymphoid. Indications for use hairy cell leukemia; chronic lymphocytic leukemia (progressive and resistant to first-line drugs for chemotherapy form); non-Hodgkin's lymphoma of low and intermediate degree of malignancy; relapsing multiple sclerosis; chronic progressive multiple sclerosis. Pharmacokinetics In CSF penetrates 25% of the drug. Undergoes intracellular metabolism. Report mostly in the urine (35%), a small amount (1%) in the faeces. Dosage and administration:in/In the drip, in the form of 2-or 24-hour infusion. The dose and duration of treatment set depending on the characteristics of the disease and the severity of the condition. The recommended dose of 0.09-0.1 mg/kg / day for 7 days. The increase in antitumor effect in the advanced courses available. Before the introduction of the necessary quantity of concentrate is diluted in 0.5 - 1 l 0.9 % sodium chloride solution for 24-h infusions using bacteriostatic 0.9 % sodium chloride solution (contains preservative benzyl alcohol)
+38 (050) 987-05-08
+38 (093) 719-31-59
+38 (067) 115-73-32 Alexander
Price 500 UAH